Give it a listen. This is the first single from the forthcoming Backspacer album, preselling on the band's website [ http://www.pearljam.com ] right now.
Thoughts: it's a new sound, but then, every album from PJ has had a different sound, and the development is really the logical next step forward from the self-titled album released in 2006. This is a group of supremely talented musicians (Vedder's vocal range is one of the most often imitated -- and poorly -- in rock, Cameron's a legendary drummer, and Rolling Stone recently named Gossard & McCready "Pearl Jam's Four-Armed Monster"). I like it... a lot... and I'm looking forward to the album itself.